| 货号: S218142 |
| 产品全名: BTNL2 兔多抗 |
| 基因符号 SS2; BTN7; BTL-II; HSBLMHC1 |
| UNIPROT ID: Q9UIR0 (Gene Accession – BC127642 ) |
| 背景: This gene encodes a major histocompatibility comple,x class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. |
| 抗原: Fusion protein of human BTNL2 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 200-400;WB: 500-2000;ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Immunology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218142(BTNL2 Antibody) at a dilution of 1/220(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218142(Anti-BTNL2 Antibody) at dilution 1/220. | 
The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 218142(Anti-BTNL2 Antibody) at a dilution of 1/220. | 
In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D223807(Anti-BTNL2 Antibody) at dilution 1/220. | 
Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse kidney tissue lysate;
Primary antibody: 218142(BTNL2 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 40 seconds | |
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