| 货号: S217879 |
| 产品全名: MAP3K7 兔多抗 |
| 基因符号 CSCF; FMD2; TAK1; MEKK7; TGF1a |
| UNIPROT ID: O43318 (Gene Accession – BC017715 ) |
| 背景: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| 抗原: Fusion protein of human MAP3K7 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 200-300;WB: 500-2000;ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction, Cardiovascular, Immunology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217879(MAP3K7 Antibody) at a dilution of 1/150(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217879(Anti-MAP3K7 Antibody) at dilution 1/150. | 
Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-5: 231, 293T, HepG2, Jurkat and K562 cell lysates;
Primary antibody: 217879(MAP3K7 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute | |
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