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DTX2 Rabbit pAb

Anti-DTX2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S216472

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S216472
产品全名:   DTX2 兔多抗
基因符号   RNF58
UNIPROT ID:   Q86UW9 (Gene Accession – BC018555 )
背景:   DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
抗原:   Fusion protein of human DTX2
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 200-400; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216472(DTX2 Antibody) at a dilution of 1/300(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216472(Anti-DTX2 Antibody) at dilution 1/300.
           引用文献