| 货号: S216261 |
| 产品全名: STAT4 兔多抗 |
| 基因符号 SLEB11 |
| UNIPROT ID: Q14765 (Gene Accession – BC031212 ) |
| 背景: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. |
| 抗原: Fusion protein of human STAT4 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 50-300;WB: 500-2000;ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction, Epigenetics and Nuclear Signaling |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 216261(STAT4 Antibody) at a dilution of 1/75(Cytoplasm and Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the fusion protein and then with 216261(Anti-STAT4 Antibody) at dilution 1/75. | 
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 216261(Anti-STAT4 Antibody) at a dilution of 1/75. | 
In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D220086(Anti-STAT4 Antibody) at dilution 1/75. | 
Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: TM4 and 293T cell lysates;
Primary antibody: 216261(STAT4 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute | |
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