武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,850.00
货号: S215925 | ||||
产品全名: GRTP1 兔多抗 | ||||
基因符号 TBC1D6 | ||||
UNIPROT ID: Q5TC63 (Gene Accession – NP_078995 ) | ||||
背景: GRTP1 (Growth hormone-regulated TBC protein 1), also designated TBC1 domain family member 6, is a 336 amino acid protein with expression modulated by growth hormone. The TBC1 domain of GRTP1 is a region that is notably conserved among GTPase-activating proteins, which characteristically play a role in the cell cycle and mitosis coordination. Interestingly, expression of GRTP1 is significantly upregulated in post-puberty testis and then maintained in the adult, suggesting that the germ cell may be the major site of GRTP1 function. There are two isoforms of GRTP1, which are a result of alternative splicing events. May act as a GTPase-activating protein for Rab family protein(s). | ||||
抗原: Synthetic peptide of human GRTP1 | ||||
经过测试的应用: ELISA, IHC | ||||
推荐稀释比: IHC: 25-50; ELISA: 5000-10000 | ||||
种属反应性: Rabbit | ||||
克隆性: Rabbit Polyclonal | ||||
亚型: Immunogen-specific rabbit IgG | ||||
纯化: Antigen affinity purification | ||||
种属反应性: Human | ||||
成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
研究领域: Signal Transduction | ||||
储存和运输: Store at -20°C. Avoid repeated freezing and thawing | ||||
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