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FCGR3A (DMC219) IgG1 Chimeric mAb

Anti-FCGR3A (DMC219) IgG1 Chimeric Monoclonal Antibody
5/5

¥445.00

货号:28168

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28168
产品全名:   FCGR3A(DMC219) IgG1 Chimeric 单抗
基因符号   FCGR3A;CD16A;FCG3;FCGR3;IGFR3
描述:   FCGR3A antibody(DMC219) IgG1 Chimeric 单抗
背景:   This gene encodes a receptor for the Fc portion of immunoglobulin G; and it is involved in the removal of antigen-antibody complexes from the circulation; as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide; whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections; susceptibility to systemic lupus erythematosus; and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
经过测试的应用:   ELISA; Flow Cyt
推荐稀释比:   ELISA 1:5000-10000; Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit:Human Fc chimeric IgG1
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 FCGR3A
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-FCGR3A (DMC219) on Expi293 cells transfected with human FCGR3A (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
           引用文献