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CD162 (DMC283) IgG1 Chimeric mAb

Anti-CD162 (DMC283) IgG1 Chimeric Monoclonal Antibody
5/5

¥445.00

货号:28191

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28191
产品全名:   CD162(DMC283) IgG1 Chimeric 单抗
基因符号   PSGL-1;PSGL1;CD162;SELPLG;Selectin P ligand
描述:   CD162 antibody(DMC283) IgG1 Chimeric 单抗
背景:   This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-; E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such; this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications; tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans; for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
经过测试的应用:   Flow Cyt
推荐稀释比:   Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit:Human Fc chimeric IgG1
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 CD162
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-CD162 (DMC283) on Expi293 cells transfected with human CD162 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
           引用文献