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CCR6 (DMC477) IgG1 Chimeric mAb

Anti-CCR6 (DMC477) IgG1 Chimeric Monoclonal Antibody
5/5

¥445.00

货号:28253

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28253
产品全名:   CCR6(DMC477) IgG1 Chimeric 单抗
基因符号   BN-1; C-C CKR-6; CC-CKR-6; CCR-6; CD196; CKR-L3; CKRL3; CMKBR6; DCR2; DRY6; GPR29; GPRCY4; STRL22
描述:   CCR6 antibody(DMC477) IgG1 Chimeric 单抗
背景:   This gene encodes a member of the beta chemokine receptor family; which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation; and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq; Jul 2008]
经过测试的应用:   Flow Cyt
推荐稀释比:   Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit:Human Fc chimeric IgG1
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 CCR6
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. CCR6 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-CCR6 (DMC477) on Expi293 cells transfected with human CCR6 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
           引用文献