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IGF1R (DMC684) IgG1 Chimeric mAb

Anti-IGF1R (DMC684) IgG1 Chimeric Monoclonal Antibody
5/5

¥445.00

货号:28282

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28282
产品全名:   IGF1R(DMC684) IgG1 Chimeric 单抗
基因符号   CD221; IGFIR; IGFR; JTK13
描述:   IGF1R antibody(DMC684) IgG1 Chimeric 单抗
背景:   This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq; May 2014]
经过测试的应用:   Flow Cyt
推荐稀释比:   Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit:Human Fc chimeric IgG1
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   人 IGF1R
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. IGF1R protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-IGF1R (DMC684) on Expi293 cells transfected with human IGF1R (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
           引用文献