武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

邮箱:info@neweastwuhan.com

咨询:027 – 63497286 

SARS-CoV-2 RBD (DM26) Rabbit mAb

Anti-SARS-CoV-2 RBD (DM26) Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:28310

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   28310
产品全名:   SARS-CoV-2 RBD(DM26) 兔单克隆抗体
基因符号   SARS-CoV-2 RBD
描述:   SARS-CoV-2 RBD antibody(DM26) 兔单克隆抗体
背景:   SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits; S1 and S2. S1 mainly contains a receptor binding domain (RBD); which accounts for recognizing the cell surface receptor; ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response.
经过测试的应用:   ELISA; Flow Cyt
推荐稀释比:   ELISA 1:5000-10000; Flow Cyt 1:100
种属反应性:   Rabbit
亚型:   Rabbit IgG
纯化:   Purified from cell culture supernatant by affinity chromatography
种属反应性:   SARS-CoV-2 S protein RBD
成分:   Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Competition flow cytometry assay demonstrating Rabbit anti-RBD monoclonal antibody ( clone: DM26) blockade of SARS-CoV-2 (COVID-19) S protein RBD (1µg/ml, [getskuurl sku=11301 binding to Expi 293 cell line transfected with human ACE2. IC50=1717ng/ml. The Y-axis represents the geometric mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
           引用文献