| 货号: 28485 |
| 产品全名: TNFSF12(DM140) 兔单克隆抗体 |
| 基因符号 TNFSF12 |
| 描述: TNFSF12 antibody(DM140) 兔单克隆抗体 |
| 背景: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14:TWEAKR receptor. This cytokine has overlapping signaling functions with TNF; but displays a much wider tissue distribution. This cytokine; which exists in both membrane-bound and secreted forms; can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells; and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977; TNFSF12-TNFSF13. |
| 经过测试的应用: ELISA; Flow Cyt |
| 推荐稀释比: ELISA 1:5000-10000; Flow Cyt 1:100 |
| 种属反应性: Rabbit |
| 亚型: Rabbit IgG |
| 纯化: Purified from cell culture supernatant by affinity chromatography |
| 种属反应性: 人 TNFSF12 |
| 成分: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
Figure 1. ELISA plate pre-coated by 1 µg/ml (100 µl/well) Human TNFSF12 protein, hFc tagged protein 11223 can bind Rabbit anti-TNFSF12 monoclonal antibody (clone: DM140) in a linear range of 5-200 ng/ml. | 
Figure 2. Flow cytometry analysis with Anti-TNFSF12 (DM140) on Expi293 cells transfected with human TNFSF12 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |
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