武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥445.00
货号: 28508 |
产品全名: CLEC12A(DM165) 兔单克隆抗体 |
基因符号 CLEC12A;MICL;CLL-1;CLL1;DCAL2;DCAL-2;CD371 |
描述: CLEC12A antibody(DM165) 兔单克隆抗体 |
背景: This gene encodes a member of the C-type lectin:C-type lectin-like domain (CTL:CTLD) superfamily. Members of this family share a common protein fold and have diverse functions; such as cell adhesion; cell-cell signaling; glycoprotein turnover; and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described; but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL:CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. |
经过测试的应用: ELISA; Flow Cyt |
推荐稀释比: ELISA 1:5000-10000; Flow Cyt 1:100 |
种属反应性: Rabbit |
亚型: Rabbit IgG |
纯化: Purified from cell culture supernatant by affinity chromatography |
种属反应性: 人 CLEC12A |
成分: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
Figure 1. Flow cytometry analysis with Anti-CLEC12A (DM165) on Expi293 cells transfected with human CLEC12A (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |