武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

邮箱:2716620741@qq.com

咨询:027 – 63497286 

Mouse CD40 Ligand Protein, hFc Tag

Recombinant mouse CD40L protein with N-terminal human Fc tag
5/5

¥550.00

货号:12192

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   12192
产品全名:   Mouse CD40 Ligand 蛋白
规格:   10/50/100 µg
基因符号   CD40-L;TRAP;CD154;Cd40lg
目标蛋白:    CD40 Ligand
UNIPROT ID:    P27548
描述:   Recombinant mouse CD40L protein with N-terminal human Fc tag
背景:     Cytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (PubMed:1374165).[UniProtKB/Swiss-Prot Function]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 42.1 kDa after removal of the signal peptide. The apparent molecular mass of hFc-CD40L is approximately 40-55 kDa due to glycosylation.
分子特征:   hFc(Glu99-Ala330) Mouse CD40 Ligand(Gly115-Leu260)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse CD40 Ligand Protein, hFc Tag on SDS-PAGE under reducing condition.
           引用文献