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Human IL-28A (C-6His) Protein

Recombinant Human Interferon Lambda-2 is produced by our Mammalian expression system and the target gene encoding Val26-Val200 is expressed with a 6His tag at the C-terminus.
5/5

¥365.00

货号:12094

规格: 50 μg

库存状态:In Stock

           产品描述          
货号:   12094
产品全名:   人 IL-28A (C-6His) 蛋白
规格:   10/50/100 µg
基因符号   Interferon lambda-2;IFN-lambda-2;Cytokine Zcyto20;Interleukin-28A;IL-28A;IFNL2;IL28A;ZCYTO20
目标蛋白:    IL-28A
UNIPROT ID:    Q8IZJ0
描述:   Recombinant Human Interferon Lambda-2 is produced by our Mammalian expression system and the target gene encoding Val26-Val200 is expressed with a 6His tag at the C-terminus.
背景:     IL-28A (Interferon-λ2? IFN-λ2), IL-28B/IFN-λ3, and IL-29/IFN-λ1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines. Mature human IL-28A is an approximately 22-25 kDa protein that shares 66% amino acid (aa) sequence identity with mouse and rat IL-28A and shows cross-species activity. It shares 96% and 70% aa sequence identity with human IL-28B and IL-29, respectively. IL-28A promotes the Th1 polarization of dendritic cells in the airway and inhibits Th2 and Th17 mediated inflammation. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo. In contrast, it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.
物种/宿主:    HEK293
分子量:   20.6 KDa
分子特征:   Not available
纯化:   Greater than 95% as determined by reducing SDS-PAGE.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
           引用文献