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Human LOX-1 Protein, hFc Tag

Recombinant Human? LOX-1 Protein with N-terminal human Fc tag
5/5

¥389.00

货号:11968

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11968
产品全名:   人 LOX-1 蛋白
规格:   10/50/100 µg
基因符号   CLEC8A;LOX1;LOXIN;SCARE1;SLOX1;OLR1
目标蛋白:    LOX-1
UNIPROT ID:    P78380
描述:   Recombinant Human LOX-1 Protein with N-terminal human Fc tag
背景:     This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 50.9 kDa after removal of the signal peptide. The apparent molecular mass of hFc-LOX-1 is approximately 55-70 kDa due to glycosylation.
分子特征:   hFc(Glu99-Ala330) LOX-1(Met58-Gln273)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human LOX-1 Protein, hFc Tag on SDS-PAGE under reducing condition.
           引用文献