| 货号: 11909 |
| 产品全名: 人 LAIR1 蛋白 |
| 规格: 10/50/100 µg |
| 基因符号 CD305;LAIR-1 |
| 目标蛋白: LAIR1 |
| UNIPROT ID: Q6GTX8 |
| 描述: Recombinant Human LAIR1 Protein with C-terminal human Fc tag |
| 背景: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| 物种/宿主: HEK293 |
| 分子量: The protein has a predicted molecular mass of 41.6 kDa after removal of the signal peptide. The apparent molecular mass of LAIR1-hFc is approximately 35-70 kDa due to glycosylation. |
| 分子特征: LAIR1(Gln22-His163) hFc(Glu99-Ala330) |
| 纯化: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1.Human LAIR1 Protein, hFc Tag on SDS-PAGE under reducing condition. |
