武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

邮箱:2716620741@qq.com

咨询:027 – 63497286 

Human CCR2 Protein, mFc Tag

Recombinant human CCR2 protein with C-terminal mouse Fc tag
5/5

¥569.00

货号:11777

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11777
产品全名:   人 CCR2 蛋白
规格:   10/50/100 µg
基因符号   CC-CKR-2;MCP-1-R;CD192
目标蛋白:    CCR2
UNIPROT ID:    P41597
描述:   Recombinant human CCR2 protein with C-terminal mouse Fc tag
背景:     The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 31.1 kDa after removal of the signal peptide. The apparent molecular mass of CCR2-mFc is approximately 35-55 kDa due to glycosylation.
分子特征:   CCR2(Met1-Ala42) mFc(Pro99-Lys330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CCR2 Protein, mFc Tag on SDS-PAGE under reducing condition.
           引用文献