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Human IL18BP Protein, hFc Tag

Recombinant human IL18BP protein with C-terminal human Fc tag
5/5

¥550.00

货号:11791

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11791
产品全名:   人 IL18BP 蛋白
规格:   10/50/100 µg
基因符号   FVH;IL18BPa
目标蛋白:    IL18BP
UNIPROT ID:    O95998
描述:   Recombinant human IL18BP protein with C-terminal human Fc tag
背景:     The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 43.8 kDa after removal of the signal peptide. The apparent molecular mass of IL18BP-hFc is approximately 53-70 kDa due to glycosylation.
分子特征:   IL18BP(Thr31-Gly194) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IL18BP Protein, hFc Tag on SDS-PAGE under reducing condition.
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