| 货号: 11377 |
| 产品全名: 人 IL11RA 蛋白 |
| 规格: 10/50/100 µg |
| 基因符号 IL-11 R alpha;L-11 RA;L11RA;nterleukin-11 receptor subunit alpha;L-11 receptor subunit alpha;L-11R subunit alpha;L-11R-alpha |
| 目标蛋白: IL11RA |
| UNIPROT ID: Q14626 |
| 描述: Recombinant Human IL11RA with C-terminal human Fc tag |
| 背景: Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] |
| 物种/宿主: HEK293 |
| 分子量: The protein has a predicted molecular mass of 44.3 kDa after removal of the signal peptide.The apparent molecular mass of IL11RA-hFc is approximately 35-55 kDa due to glycosylation. |
| 分子特征: IL11RA(Ser24-Ala370) hFc(Glu99-Ala330) |
| 纯化: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human IL11RA Protein, hFc Tag on SDS-PAGE under reducing condition. |
