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Mouse BTLA Protein, mFc Tag

Recombinant mouse BTLA protein with C-terminal mFc tag
5/5

¥445.00

货号:11325

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11325
产品全名:   Mouse BTLA 蛋白
规格:   10/50/100 µg
基因符号   BTLA;D272
目标蛋白:    BTLA
UNIPROT ID:    Q7TSA3
描述:   Recombinant mouse BTLA protein with C-terminal mFc tag
背景:     Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044).
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 42.7 kDa after removal of the signal peptide.The apparent molecular mass of Mouse-BTLA-mFc is approximately 55-70 kDa due to glycosylation.
分子特征:   Mouse BTLA(Glu30-Pro176) mFc(Pro99-Lys330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse BTLA Protein, mFc Tag on SDS-PAGE under reducing condition.
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