武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥389.00
货号: 11303 |
产品全名: 人 IgG1-Fc 蛋白 |
规格: 10/50/100 µg |
基因符号 IgG1 Fc 蛋白 |
目标蛋白: IgG1-Fc |
UNIPROT ID: P01857 |
描述: Recombinant Human IgG1-Fc 蛋白 |
背景: IGHG1 (Immunoglobulin Heavy Constant Gamma 1 (G1m Marker)) is a Protein Coding gene. Diseases associated with IGHG1 include?Leukemia, Chronic Lymphocytic?and?Heavy Chain Deposition Disease. Among its related pathways are?Interleukin-4 and 13 signaling?and?IL4-mediated signaling events. Gene Ontology (GO) annotations related to this gene include?antigen binding. An important paralog of this gene is?IGHG3. |
物种/宿主: HEK293 |
分子量: The protein has a predicted molecular mass of 27.7 kDa after removal of the signal peptide.The apparent molecular mass of IgG1-Fc is approximately 30-40 kDa due to glycosylation. |
分子特征: hFc(Glu99-Ala330) |
纯化: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human IgG1-Fc Protein on SDS-PAGE under reducing condition. |