武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥4,800.00
产品名称: PTEN (R130G)货号:: 26312基因符号: PTEN, 10q23del, BZS, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1, MMAC1, PTEN1, TEP1描述: PTEN (R130G) Mouse Monoclonal Antibody背景: Phosphatase and tensin homolog (PTEN) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency.I t is one of the most commonly lost tumor suppressors in human cancer. During tumor development, mutations and deletions of PTEN occur that inactivateits enzymatic activity leading to increased cell proliferation and reduced cell death. Frequent genetic inactivation of PTEN occurs in glioblastoma, endometrial cancer,and prostate cancer; and reduced expressionis found in many other tumor types such as lung and breast cancer.Immunogen: A synthetic peptide from the internal region of PTEN which includes the mutation of R130G, human origin.Tested applications: ELISA, WB推荐稀释比:ELISA: 1:1000-1:5000WB: 1:500-1:1000Concentration: 1 mg/ml种属反应性: Mouse克隆性: Monoclonal纯化: Purified from ascites形式: LiquidStorage buffer: Preservative: no成分: PBS (without Mg2+ and Ca2+),pH 7.4, 150 mM NaCl, 50% glycerol种属反应性: Recognizes R130G mutant,but not wild type PTEN from vertebrates.储存条件: Store at -20°C. Avoid蛋白质印迹:Western blot analysis of recombinant PTEN R130G) and wild type proteins. Purified His-tagged FGFR1 (R130G) protein (lane 2) and corresponding wild type protein (lane 1) were blotted with anti-PTEN (R130G) monoclonal antibody (货号:26312).
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