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ATM(F858L)

Anti-ATM(F858L) Mouse Monoclonal Antibody
5/5

¥4,800.00

货号：26141

规格： 100 微升

库存状态：In Stock

           产品描述          
产品名称:   ATM(F858L) 小鼠单抗
货号:   26141
基因符号:   ATM
描述:   ATM(F858L) 小鼠单抗
背景:   Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activity of ATM protein is under tight control, and mutation of ATM can cause disease such as Ataxia telangiectasia (AT) and cancers.
免疫原 :    A synthetic peptide from the internal region of ATM which includes the mutation of F858L, human origin.
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   
ELISA: 1:1000-1:5000
WB: 1:100-1:1000
IHC: 1:50-1:100
Concentration:   1 mg/ml
种属反应性:   Mouse
形式:   Liquid
克隆性：  Monoclonal
亚型:   IgG
纯化:   Purified from ascites
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:   Recognizes ATM(F858L), but not wild type ATM protein from vertebrates.
储存条件:    Store at -20°C. Avoid repeated freezing and thawing
蛋白质印迹:   

Western blot analysis of recombinant ATM(F858L) and wild type proteins. Purified His-tagged ATM(F858L) protein (amino acids 2400-3056, lane 2) and corresponding wild type protein (lane 1) were blotted with Anti-ATM(F858L) 小鼠单抗 (货号:26141).

Immunofluorescence:   

Immunofluorescence of cells expressing ATM(F858L) protein with anti-ATM(F858L) antibody. HEK293T cells were transfected with pCDNA3-GFP-ATM (WT) plasmid (left column) or pCDNA3-GFP-ATM(F858L) plasmid (right column), then fixed and stained with Anti-ATM(F858L) monoclonal antibody (货号:26141).

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