| 货号: S217963 |
| 产品全名: TXNDC5 兔多抗 |
| 基因符号 HCC2; ERP46; HCC-2; STRF8; PDIA15; UNQ364; ENDOPDI |
| UNIPROT ID: Q8NBS9 (Gene Accession – BC052310 ) |
| 背景: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene. |
| 抗原: Fusion protein of human TXNDC5 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 200-400;WB: 500-2000;ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction, Cancer |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 217963(TXNDC5 Antibody) at a dilution of 1/180(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 217963(Anti-TXNDC5 Antibody) at dilution 1/180. | 
Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-4: HT29, 293T, Hela cell, Human placenta tissue lysates;
Primary antibody: 217963(TXNDC5 Antibody) at dilution 1/1350;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds | |
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