| 货号: S219512 |
| 产品全名: TDRD3 兔多抗 |
| 基因符号 |
| UNIPROT ID: Q9H7E2 (Gene Accession – BC030514 ) |
| 背景: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. |
| 抗原: Fusion protein of human TDRD3 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 200-300;WB: 500-2000;ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Epigenetics and Nuclear Signaling, Neuroscience |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 219512(TDRD3 Antibody) at a dilution of 1/150(Nucleus and Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 219512(Anti-TDRD3 Antibody) at dilution 1/150. | 
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 219512(Anti-TDRD3 Antibody) at a dilution of 1/150. | 
In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D227443(Anti-TDRD3 Antibody) at dilution 1/150. | 
Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: HUVEC, NIH/3T3, MCF-7 cell lysates;
Primary antibody: 219512(TDRD3 Antibody) at dilution 1/700;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 30 seconds | |
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