武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CCM2 Rabbit pAb

Anti-CCM2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S212176

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S212176
产品全名:   CCM2 兔多抗
基因符号   OSM; C7orf22; PP10187
UNIPROT ID:   Q9BSQ5 (Gene Accession – BC004903 )
背景:   This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
抗原:   Fusion protein of human CCM2
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 20-100; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 212176(CCM2 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 212176(Anti-CCM2 Antibody) at dilution 1/30.
           引用文献