武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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BAGE2 Rabbit pAb

Anti-BAGE2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S221606

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S221606
产品全名:   BAGE2 兔多抗
基因符号   CT2.2
UNIPROT ID:   Q86Y30
背景:   Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2(B melanoma antigen 2), also known as Cancer/testis antigen 2.2, is 109 amino acid secreted proteins that is expressed in 22% of melanomas, lung and bladder carcinomas, and is also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
抗原:   Synthetic peptide of human BAGE2
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 221606(BAGE2 Antibody) at a dilution of 1/25(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 221606(Anti-BAGE2 Antibody) at dilution 1/25.
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