武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,850.00
货号: N261862 | ||
产品全名: Aprataxin 兔单克隆抗体 | ||
基因符号 AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT | ||
UNIPROT ID: Q7Z2E3 | ||
背景: DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair (PubMed:15380105, PubMed:15044383, PubMed:16964241, PubMed:17276982, PubMed:24362567). Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species (PubMed:16964241, PubMed:24362567). Catalyzes the release of adenylate groups covalently linked to 5′-phosphate termini, resulting in the production of 5′-phosphate termini that can be efficiently rejoined (PubMed:16964241, PubMed:17276982, PubMed:24362567). Also able to hydrolyze adenosine 5′-monophosphoramidate (AMP-NH2) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (PubMed:16547001). Likewise, catalyzes the release of 3′-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5′-linked adenosine (AppDNA) . | ||
抗原: A synthetic peptide of human Aprataxin | ||
经过测试的应用: WB,ICC/IF | ||
推荐稀释比: WB: 1/500-1/1000 IF: 1/50-1/200 | ||
种属反应性: Rabbit | ||
克隆性: Rabbit Monoclonal | ||
克隆编号: R03-9F6 | ||
分子量: Calculated MW: 41 kDa; Observed MW: 41 kDa | ||
亚型: IgG | ||
纯化: Affinity Purified | ||
种属反应性: Human | ||
成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
研究领域: Epigenetics and Nuclear Signaling | ||
储存和运输: Store at -20°C. Avoid repeated freezing and thawing | ||
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