| 货号: S216244 |
| 产品全名: ALPL 兔多抗 |
| 基因符号 HOPS; TNAP; TNALP; APTNAP; TNSALP; AP-TNAP |
| UNIPROT ID: P05186 (Gene Accession – BC110909 ) |
| 背景: This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. |
| 抗原: Fusion protein of human ALPL |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 200-400; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Cancer |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 216244(ALPL Antibody) at a dilution of 1/240(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 216244(Anti-ALPL Antibody) at dilution 1/240. | 
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 216244(Anti-ALPL Antibody) at a dilution of 1/240. | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D220062(Anti-ALPL Antibody) at dilution 1/240. |
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