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ATM Rabbit mAb

Anti-ATM Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N261751

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261751
产品全名:   ATM 兔单克隆抗体
基因符号   ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated
UNIPROT ID:   Q13315
背景:   The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.
抗原:   Recombinant protein of human ATM
经过测试的应用:   WB,IP,ChIP
推荐稀释比:   WB: 1/500-1/1000 IP: 1/20 ChIP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R05-8D4
分子量:   Calculated MW: 351 kDa; Observed MW: 351 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of ATM in Hela lysates using ATM antibody.
           引用文献