武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,850.00
货号: N226075 |
产品全名: Phospho-SIRT1 (Ser47) 兔多抗 |
基因符号 SIRT1; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2 |
UNIPROT ID: Q96EB6 |
背景: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. |
抗原: A synthetic phosphopeptide corresponding to residues surrounding Ser47 of human SIRT1 |
经过测试的应用: WB,IHC-F,IHC-P,ICC/IF |
推荐稀释比: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 |
种属反应性: Rabbit |
克隆性: Rabbit Polyclonal |
分子量: Calculated MW: 82 kDa; Observed MW: 120 kDa |
亚型: IgG |
纯化: Affinity Purified |
种属反应性: Human |
Modification: Phosphorylated |
成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
研究领域: Cell Biology |
储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of Phospho-SIRT1(Ser47) in A549 lysates using Phospho-SIRT1 (Ser47) antibody. |