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Cleaved-Notch1 Rabbit pAb

Anti-Cleaved-Notch1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225351

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225351
产品全名:   Cleaved-Notch1 兔多抗
基因符号   NOTCH1; TAN1; Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1
UNIPROT ID:   P46531
背景:   Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.
抗原:   The antiserum was produced against synthesized peptide derived from human Notch 1. AA range:1735-1784
经过测试的应用:   WB,ICC/IF,IHC-F,IHC-P,ELISA
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 273 kDa; Observed MW: 110 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
Modification:   Cleaved
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Cleaved-Notch1 in various lysates using Cleaved-Notch1 antibody.
           引用文献