| 货号: S220318 |
| 产品全名: CD44 兔多抗 |
| 基因符号 IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III |
| UNIPROT ID: P16070 (Gene Accession – NP_000601 ) |
| 背景: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. |
| 抗原: Synthetic peptide of human CD44 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 50-100; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Cancer, Immunology, Stem Cells |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human gastric cancer using 220318(CD44 Antibody) at a dilution of 1/45(Cell membrane). | 
In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer is first treated with the synthetic peptide and then with 220318(Anti-CD44 Antibody) at dilution 1/45. | 
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer using 220318(Anti-CD44 Antibody) at a dilution of 1/45. | 
In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer is first treated with synthetic peptide and then with D261338(Anti-CD44 Antibody) at dilution 1/45. |
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