武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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JPT1 Rabbit pAb

Anti-JPT1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218975

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218975
产品全名:   JPT1 兔多抗
基因符号   HN1; ARM2; HN1A
UNIPROT ID:   Q9UK76 (Gene Accession – BC001420 )
背景:   Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 ‘Ser-33’ phosphorylation and degradation through the suppression of the inhibitory ‘Ser-9’ phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).
抗原:   Fusion protein of human JPT1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 40-200; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 218975(JPT1 Antibody) at a dilution of 1/35(Nucleus and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 218975(Anti-JPT1 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 218975(Anti-JPT1 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D225592(Anti-JPT1 Antibody) at dilution 1/35.
           引用文献