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NSMCE2 Rabbit pAb

Anti-NSMCE2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218210

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218210
产品全名:   NSMCE2 兔多抗
基因符号   NSE2; MMS21; ZMIZ7; C8orf36
UNIPROT ID:   Q96MF7 (Gene Accession – BC032797 )
背景:   NSMCE2 is the E3 SUMO-protein ligase component of the SMC5-SMC6 comple,x a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. NSMCE2 acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRA,x and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.
抗原:   Full length fusion 蛋白
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218210(NSMCE2 Antibody) at a dilution of 1/25(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218210(Anti-NSMCE2 Antibody) at dilution 1/25.
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