武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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MEI1 Rabbit pAb

Anti-MEI1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217598

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217598
产品全名:   MEI1 兔多抗
基因符号   SPATA38
UNIPROT ID:   Q5TIA1 (Gene Accession – BC032248 )
背景:   The predominant cause of spermatogenic arrest of meiosis is the failure of homologous chromosomes to accurately synapse. MEI1 (Meiosis inhibitor protein 1), also designated Meiosis defective protein 1, is a 1274 amino acid protein that is likely required for the formation of genetically programmed double-strand breaks, the first step in the initiation of meiosis. With predominant expression in testis, it is likely that defects of the gene encoding MEI1 results in male infertility. Interestingly, studies show that genetic variation in the MEI gene possibly predisposes European Americans but not Israeli men to infertility by meiotic arrest. Human MEI1 shares 79% sequence similarity with its mouse homolog. There are seven isoforms of MEI1 that are produced as a result of alternative splicing events.
抗原:   Fusion protein of human MEI1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 1000-2000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cancer, Stem Cells
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217598(MEI1 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217598(Anti-MEI1 Antibody) at dilution 1/20.
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