武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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IGF1R Rabbit pAb

Anti-IGF1R Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S215206

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S215206
产品全名:   IGF1R 兔多抗
基因符号   IGFR; CD221; IGFIR; JTK13
UNIPROT ID:   P08069 (Gene Accession – NP_000866 )
背景:   This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
抗原:   Synthetic peptide of human IGF1R
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 20-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Cancer, Developmental Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 215206(IGF1R Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 215206(Anti-IGF1R Antibody) at dilution 1/30.
           引用文献