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CBFA2T2 Rabbit pAb

Anti-CBFA2T2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S212856

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S212856
产品全名:   CBFA2T2 兔多抗
基因符号   EHT; p85; MTGR1; ZMYND3
UNIPROT ID:   O43439 (Gene Accession – BC040344 )
背景:   In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5′-region of the RUNX1 (AML1) gene fused to the 3′-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.
抗原:   Fusion protein of human CBFA2T2
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-300; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 212856(CBFA2T2 Antibody) at a dilution of 1/60(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 212856(Anti-CBFA2T2 Antibody) at dilution 1/60.
           引用文献